In the second round of the Rugby Championship, South Africa will attempt to achieve a feat against New Zealand they have managed just twice.
Brad Shields has been sent for tests on a foot injury, with Alex Dombrandt called up to the England training camp in his place.
Australia are welcoming back Christian Lealiifano and James O'Connor for their clash against Argentina.
New Zealand have moved Beauden Barrett to full-back for their meeting with South Africa.
Rassie Erasmus has made 12 changes to his team as South Africa prepare for New Zealand, with Duane Vermeulen captain against the All Blacks.
Will Genia believes James O'Connor will grasp his chance if a six-year Wallabies exile comes to an end when Australia face Argentina.
Head coach Steve Hansen is relishing what promises to be another almighty battle with South Africa this weekend.
Joe Marchant is among the 38 players who have made the trip to Italy as England step up their preparations for the Rugby World...
Read more
The fourteen South Africa players who flew to New Zealand on Thursday will be joined by another 22.
Head coach Steve Hansen says New Zealand's less-experienced players will learn from a huge battle with Argentina.
Argentina pushed New Zealand all the way in Buenos Aires, and All Blacks star Ardie Savea agreed the contest felt like war at times.
Argentina kept New Zealand scoreless for the second half of their Buenos Aires showdown, but could not avoid a Rugby Championship defeat.
Michael Hooper admitted Australia have a lot of things to work on following their 35-17 Rugby Championship defeat to South Africa.