Clermont Auvergne suffered a derby defeat to Top 14 new boys Brive as defending champions Toulouse earned their first win of the season.
A knee sprain sustained in South Africa's win over Japan on Friday will not stop Trevor Nyakane being ready for the Rugby World Cup.
The top two in the Top 14 both triumphed on Saturday, with Bordeaux-Begles and Lyon improving to three wins from three this season.
The Lions almost repeated August's Currie Cup fightback against the Cheetahs in Saturday's final, falling short as their opponents held on.
Wales avoided a repeat of 2015's pre-Rugby World Cup injury problems as Ireland won 19-10 in Dublin on Saturday to take the No.1 ranking.
Michael Cheika's Wallabies head into the Rugby World Cup with no new injury concerns after getting through unscathed against Samoa.
Eddie Jones does not expect to have Mako Vunipola available until England face Argentina or France in the Rugby World Cup pool stage.
With New Zealand leading Tonga 92-0, Steve Hansen opted to save Ryan Crotty and play the last 15 minutes a man light.
The All Blacks fell just short of 100 points in a merciless display in Hamilton, where New Zealand scored 14 tries on Saturday.
Captain Owen Farrell converted all four of England's tries and also kicked three penalties as his side eased past Italy on Friday.
Gregor Townsend may count the cost of injuries from Scotland's final Rugby World Cup warm-up victory over Georgia.
One of the best wings in South African rugby history, World Cup winner Chester Williams died on Friday.
Japan were unable to repeat their shock 2015 Rugby World Cup success over South Africa, largely due to Makazole Mapimpi's hat-trick.
The upcoming Rugby World Cup will mark David Pocock's last matches for the Wallabies.
Ireland have been boosted by the returns of Johnny Sexton, Conor Murray, Keith Earls and Robbie Henshaw for their meeting with Wales.
Wales have rung the changes against Ireland as they finish preparations for the Rugby World Cup.