Bordeaux Begles gave another demonstration of their Top 14 title credentials with a bonus-point win over Clermont Auvergne.
Top 14 front-runners Lyon won again, while La Rochelle's Arthur Retiere grabbed a hat-trick and Brive left it late.
High-flying pair Lyon and Bordeaux Begles celebrated contrasting victories in Top 14 action on Saturday.
There were wins for Lyon and Racing 92 in the Top 14 as Bordeaux-Begles were usurped at the summit.
Handre Pollard missed some crucial kicks on his Montpellier debut while Top 14 leaders Lyon
Toulouse have hit form and made light work of Bayonne at home, while Brive defeated Stade Francais.
Toulouse's contrasting home and away form continued as they defeated visitors and 2018-19 Top 14 final opponents Clermont Auvergne.
An early red card was decisive as Bordeaux-Begles suffered their second defeat of the Top 14 season.
It was another game and another win for Lyon in Top 14, where Castres were defeated by Toulouse on Saturday.
Leaders Lyon are the only unbeaten side in the Top 14 after they won a top-of-the-table encounter against Bordeaux-Begles.
Despite seeing their try line breached for the first time this season, Lyon maintained a 100 per cent start to the season in the... Read more
The top two in the Top 14 claimed huge victories to stay unbeaten as both the defending champions and last year's runners-up were beaten.
Clermont Auvergne suffered a derby defeat to Top 14 new boys Brive as defending champions Toulouse earned their first win of the season.
The second round of Top 14 fixtures saw hard-fought wins for Clermont Auvergne, La Rochelle and Montpellier, among others, on Saturday.
There were shock wins for Bayonne and Bordeaux-Begles as the Top 14 returned for the 2019-20 season on Saturday.
Brive have announced the signing of Stuart Olding, who was released by Ulster last month despite his acquittal in a rape trial.