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Saracens may be heading to the second tier but Owen Farrell is staying put, the fly-half opting to remain at Allianz Park.
Maro Itoje and Mako Vunipola have not committed to Saracens for next season, but John Mitchell is confident they will make the right call.
England overlook Mako Vunipola as a coronavirus precaution, yet he will play for Saracens against Leicester Tigers.
Mako Vunipola could play for Saracens this weekend, but England were advised not to take any risks following the prop's trip overseas.
Saracens have clarified Mako Vunipola has not been in self-isolation and is free to play Leicester Tigers this weekend.
Initially ruled out of the Wales Six Nations game for "medical reasons", England confirmed Mako Vunipola is in self-isolation.
England will not have Mako Vunipola back to face Wales, with the prop ruled out for the Six Nations encounter at Twickenham.
England prop Mako Vunipola features in their 34-man squad ahead of the game with Wales, with Jack Maunder called up.
Absent for the opening three matches of the Six Nations, Anthony Watson is back in the mix for England this week.
Mako Vunipola has flown to Tonga and will not be available for England's Six Nations encounter with unbeaten Ireland this weekend.
England were humbled by France in their Six Nations opener and Eddie Jones could be set to make changes for the clash with Scotland.
It remains to be seen whether Saracens lose some of their star players, but director of rugby Mark McCall is keen to stay with the club.
Owen Farrell, Maro Itoje and the Vunipola brothers will all likely become available after Saracens were relegated from the Premiership.
Brothers Billy and Mako Vunipola played starring roles as reigning champions Saracens defeated Munster in the European Champions Cup.
England must show no fear in the Rugby World Cup final, says Eddie Jones, who has backed his side to take the game to South Africa.
The psychological games have already begun as England and South Africa prepare to contest the Rugby World Cup final on Saturday.
