Exeter plundered eight tries in a crushing victory over Northampton as they took another step closer to finishing top of the Premiership.
Henry Purdy and Lewis Thiede touched down within two minutes of one another to see Bristol Bears past Northampton Saints.
Northampton Saints looked to be heading top of the Premiership until London Irish sprung a shock following Api Ratuniyarawa's dismissal.
Cobus Reinach could be set to join Montpellier after announcing he will leave Northampton Saints following three seasons at the club.
A thrashing of Lyon ensured Leinster made it five wins from five in the European Champions Cup, while Racing 92 reached the last eight.
Sam Hill and Gareth Steenson starred for Exeter in their win over London Irish, while Taqele Naiyaravoro was the hero for Northampton.
Munster put in a monumental effort, but Leinster's defence refused to buckle at Thomond Park.
Northampton Saints defeated Gloucester in a barnstorming contest at Franklin's Gardens, while Sale Sharks overcame Bath in the Premiership.
Saracens won a fifth straight Premiership match, though they are still far behind Leicester Tigers, who were defeated by Exeter Chiefs.
Northampton Saints made it four wins from five to go top of the Premiership, while Exeter Chiefs thrashed Wasps.
Racing 92, Northampton Saints and Connacht were all winners in Sunday's European Rugby Champions Cup action.
A looming points deduction would see Saracens facing a Premiership relegation battle this season, but they defeated Gloucester on Saturday.
A troublesome knee injury has ended Northampton Saints and England hooker Dylan Hartley's career at the age of 33.
Taqele Naiyaravoro impressed again as Northampton maintained their winning start to the Premiership season on Friday.
Northampton Saints claimed a win over the reigning champions at Allianz Park on the opening weekend of the Premiership season.
MMA promotion Bellator has signed former England rugby union star James Haskell, who is expected to make his debut in 2020.