Head coach Eddie Jones says England must look after themselves on what will be a tense final weekend of the Six Nations season.
Scotland dominated the second half at Murrayfield and Warren Gatland admitted his Wales side got "a little bit lucky" as they prevailed.
Victory over Ireland in the final round of the Six Nations would secure a Grand Slam for Wales after Warren Gatland's men overcame Scotland.
Lewis Moody says England will be wounded from a defeat to Wales that he says should never have happened.
Scott Hastings says it is time Scotland did themselves justice when they face Six Nations leaders Wales at Murrayfield.
Captain Alun Wyn Jones says the Wales squad have been affected by talk of a merger between the Scarlets and the Ospreys, which is now off.
The fourth round of fixtures in the 2019 Six Nations sees Wales visit Scotland, England take on Italy and Ireland host France.
Ali Price replaces captain Greig Laidlaw as one of four changes to the Scotland side to take on leaders Wales.
Warren Gatland wants Wales to focus on winning the Six Nations, but says talk of an Ospreys-Scarlets merger has had an impact on players.
Cory Hill's ankle injury has given Adam Beard an opportunity to come back into the Wales starting line-up at Murrayfield.
Scott Hastings says the onus is on Greig Laidlaw and other senior Scotland players to step up when they lock horns with Wales.
Scotland will once more be without full-back Stuart Hogg when they take on Wales in the Six Nations this weekend.
Cory Hill was injured while scoring a try which set Wales on their way to beating England in Cardiff and will not face Scotland or Ireland.
Warren Gatland hailed his "special" Wales players after they claimed a record 12th consecutive win at the expense of England.
England's defeat to Wales in the Six Nations was decided by "small margins" and their ill-discipline proved costly, says Eddie Jones.
Wales came from 10-3 down at half-time to claim a record 12th consecutive victory and go top of the Six Nations table.