Cory Hill's ankle injury has given Adam Beard an opportunity to come back into the Wales starting line-up at Murrayfield.
Scott Hastings says the onus is on Greig Laidlaw and other senior Scotland players to step up when they lock horns with Wales.
Scotland will once more be without full-back Stuart Hogg when they take on Wales in the Six Nations this weekend.
Cory Hill was injured while scoring a try which set Wales on their way to beating England in Cardiff and will not face Scotland...
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Warren Gatland hailed his "special" Wales players after they claimed a record 12th consecutive win at the expense of England.
England's defeat to Wales in the Six Nations was decided by "small margins" and their ill-discipline proved costly, says Eddie Jones.
Wales came from 10-3 down at half-time to claim a record 12th consecutive victory and go top of the Six Nations table.
Wales full-back Leigh Halfpenny will play for the first time since November when the Scarlets take on the Cheetahs.
Warren Gatland says it will be a "big challenge" for Kyle Sinckler to avoid getting in hot water at the Principality Stadium.
The third round of fixtures in the 2019 Six Nations sees Wales host England, Scotland visit France, and Ireland head to Italy.
Eddie Jones described Warren Gatland's team as "the greatest Welsh side ever", but the Wales coach does not agree.
Gareth Anscombe gets the nod at number 10 in a much-changed Wales side for a huge encounter with England.
Mako Vunipola and Chris Ashton are replaced by Ben Moon and Jack Nowell in England's starting line-up to take on Wales.
England's Steve Borthwick has confirmed that Maro Itoje will be absent again when they travel to Wales on Saturday.
Wales are hopeful that Leigh Halfpenny and Dan Biggar will recover in time to face England in the Six Nations on Saturday.
A minor calf strain means Chris Ashton will miss England's trip to face Wales in the Six Nations.