With this year's Six Nations looming, England fly-half Owen Farrell is expected to be out for up to 10 days after surgery on a thumb injury.
Saracens and Racing 92 secured home quarter-finals in the Champions Cup but the hopes of Exeter Chiefs are over after defeat at Munster.
For the second time in two days, a side racked up a century of points in the Challenge Cup as Bristol Bears routed Enisei 107-19.
At the age of just 28, former Springbok Patrick Lambie has retired from professional rugby, his club Racing 92 have announced.
England's preparations for the Six Nations have been hit by the fact captain Owen Farrell needs surgery.