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Chris Ashton has returned to London to join Harlequins after his Sale Sharks contract was terminated.
Saracens have clarified Mako Vunipola has not been in self-isolation and is free to play Leicester Tigers this weekend.
Experienced duo Dan Biggar and Liam Williams are on course to be fit for Wales' showdown with England at Twickenham.
Initially ruled out of the Wales Six Nations game for "medical reasons", England confirmed Mako Vunipola is in self-isolation.
England will not have Mako Vunipola back to face Wales, with the prop ruled out for the Six Nations encounter at Twickenham.
Aside from what could maybe be excused as an injury-induced hiccup against the Hurricanes, the Sharks were brilliant on tour, winning 3/4, and promised a lot...
Ireland's clash with Italy in Dublin is the only Six Nations match to be postponed due to the coronavirus.
Nemani Nadolo will be in Leicester Tigers colours next season after the Premiership club lured the former Fiji powerhouse from Montpellier.
England prop Mako Vunipola features in their 34-man squad ahead of the game with Wales, with Jack Maunder called up.
Chris Ashton is on the market after Premiership contenders Sale Sharks reached an agreement with the wing to terminate his contract early.
