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England must show they have a mature mentality if they are to defeat Scotland and clinch the Calcutta Cup, says Courtney Lawes.
Dewi Lake and Taine Basham will be hoping to make their Wales debuts against Ireland after they were called up to the squad.
Ireland's James Ryan is hungry for more honours with club and country after signing a new deal.
England will again have to cope without Anthony Watson as they look to bounce back from defeat to France in their Six Nations opener.
Defending champions Wales will have to do without Liam Williams for at least another two Six Nations matches.
Injuries sustained by Garry Ringrose and Caelan Doris open the door for Robbie Henshaw and Peter O'Mahony to start against Wales.
Eddie Jones confirmed Manu Tuilagi will not face Scotland, but is hopeful the centre will take on Ireland at Twickenham.
Writing for SA Rugby Magazine former Springbok James Dalton reflects on the respective outings of the various South African teams in Vodacom Super Rugby this past...
Tom Curry looks certain to continue at number eight for the foreseeable future and earned the backing of England coach Eddie Jones.
In-form Harlequins number eight Alex Dombrandt will play no part in the Calcutta Cup clash after being left out of England's squad.
