All Blacks captain Kieran Read says potentially losing world number one status is "not even part of our equation".
Eddie Jones has given some potential Rugby World Cup bolters a chance to show what they can do against Wales.
After taking his first NFL carry 65 yards for a touchdown, former rugby union star Christian Wade almost forgot which sport he was playing.
Australia will be looking to pull off a shock by beating their trans-Tasman rivals in the Bledisloe Cup opener in Perth.
Michael Cheika and Steve Hansen have played down comments the All Blacks head coach made about his opposite number.
Australia have opted to make four changes to their starting team to face New Zealand, with James O'Connor to start.
New Zealand made six changes to their starting side to face Australia, with Ardie Savea making a surprise positional switch.
South Africa will be aided by the vast experience of Tendai Mtawarira, who will equal a Springboks record, when they take on Argentina.
Captain Rory Best says Ireland are hungry to show their Six Nations failure was merely a blip as they prepare for the Rugby World Cup.
Argentina have made five changes for their meeting with South Africa as Benjamin Urdapilleta prepares for an international return.