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Maro Itoje will be unable to aid England's bid to win the Six Nations after injury ruled him out of the Scotland game.
Ireland's bonus-point win over France was Joe Schmidt's final home Six Nations game at the helm and he was feeling emotional afterwards.
Ireland's bonus-point win over France kept them in the hunt to defend their title in what will be Rory Best's final Six Nations outing.
Joe Schmidt's Ireland earned a bonus point in their win over France to ensure the Six Nations finale will feature a three-way title tussle.
Having suffered defeat to Bristol last time out, Gloucester responded in emphatic fashion with a resounding away win over Harlequins.
With Italy losing their last 21 Six Nations outings, Eddie Jones feels organisers should discuss changes to the tournament's structure.
England scored eight tries in a rout, but Italy head coach Conor O'Shea said: "I wouldn't get too carried away with the scoreline."
Head coach Eddie Jones says England must look after themselves on what will be a tense final weekend of the Six Nations season.
Brett Connon held his nerve with a late penalty to give Newcastle victory at Wasps, while Exeter also did the Falcons a favour.
The Bulls went top of the South African Conference by brushing aside the Sharks as the Lions held off the Jaguares.
