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Despite suffering a hamstring problem in training, Ireland centre Robbie Henshaw will not be heading home early from Japan.
We take a look at five top players who might consider themselves unfortunate to miss the Rugby World Cup in Japan.
Wales avoided a repeat of 2015's pre-Rugby World Cup injury problems as Ireland won 19-10 in Dublin on Saturday to take the No.1 ranking.
Ireland have been boosted by the returns of Johnny Sexton, Conor Murray, Keith Earls and Robbie Henshaw for their meeting with Wales.
Wales have rung the changes against Ireland as they finish preparations for the Rugby World Cup.
Ireland's talisman Johnny Sexton says he was "blessed' to overcome a thumb injury in time to make Joe Schmidt's Rugby World Cup squad.
Ireland coach Joe Schmidt has named his squad for the Rugby World Cup, with experienced second row Devin Toner surprisingly missing out.
Cory Hill is struggling with a leg fracture on the eve of Wales' Rugby World Cup squad announcement.
Jacob Stockdale scored twice as Ireland improved to beat Wales in a hard-fought affair in Cardiff on Saturday, ahead of the Rugby World Cup.
Ireland travel to Cardiff on Saturday for a Rugby World Cup warm-up match, with Josh Navidi set to captain Wales for the first time.
Jarrod Evans and Rhys Patchell will each get a chance to earn a fly-half berth in Wales' Rugby World Cup squad against Ireland.
Ireland have not matched the standards set in 2018, but Brian O'Driscoll believes they can hit form ahead of the Rugby World Cup.
Rory Best will prove his critics wrong with his calm leadership as Ireland go through a tough spell, says Jamie Heaslip.
Mako Vunipola's return from injury was cut short, but England coach Eddie Jones is "cautiously optimistic" over the prop.
The Rugby World Cup is not far away but Ireland's performance against England showed they are not ready, according to Rory Best.
Ireland's hopes of moving to the top of the world rankings on Saturday were crushed by a brilliant England display at Twickenham.
