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For the first time in over a year, George Ford and Owen Farrell will be in England's starting line-up when they face Ireland.
Ross Byrne will start Ireland's meeting with England at fly-half as Johnny Sexton and Joey Carbery struggle with injury.
Fly-half Joey Carbery should be included in Ireland's Rugby World Cup squad as his ankle injury is not as serious as first feared.
Ireland fly-half Joey Carbery was outstanding before doing damage to his left ankle in a ruck against Italy on Saturday.
Fly-half Joey Carbery impressed before damaging his ankle in Ireland's victory over Italy in Dublin.
Captain Rory Best says Ireland are hungry to show their Six Nations failure was merely a blip as they prepare for the Rugby World Cup.
Former Ireland centre Brian O'Driscoll has heaped praise on coach Joe Schmidt and says Andy Farrell is the right man to replace him.
Ireland's most decorated player, Rob Kearney, is sure of playing his 15th professional season in his home country.
Sean O'Brien, who will join London Irish later this year, is to miss the Rugby World Cup for Ireland with a hip injury.
Cian Healy says he is "part of something bigger than just a rugby team" representing Leinster and Ireland.
Paddy Jackson will leave Perpignan after a single campaign in France, joining London Irish for their return to the Premiership.
Robin McBryde will join Leinster's coaching staff as a replacement for John Fogarty, who has landed a new role with Ireland.
After a distinguished career with Ulster and Ireland, Rory Best will call time on his rugby union career after the World Cup.
Brian O'Driscoll knows Ireland need Johnny Sexton to be fit and firing if they are to make an impact at the Rugby World Cup in Japan.
Rory Best has been told he could be out for six weeks, but the hooker has described that as a "magical figure".
Ahead of the 2019-20 season, Ulster have completed a sensational swoop for Ireland prop Jack McGrath from Leinster.
