The fourth round of fixtures in the 2019 Six Nations sees Wales visit Scotland, England take on Italy and Ireland host France.
Ali Price replaces captain Greig Laidlaw as one of four changes to the Scotland side to take on leaders Wales.
Cory Hill's ankle injury has given Adam Beard an opportunity to come back into the Wales starting line-up at Murrayfield.
Scott Hastings says the onus is on Greig Laidlaw and other senior Scotland players to step up when they lock horns with Wales.
Scotland will once more be without full-back Stuart Hogg when they take on Wales in the Six Nations this weekend.
Having been thrashed by England last time out, a much-changed France side produced a fine showing to down Scotland in Paris.
The third round of fixtures in the 2019 Six Nations sees Wales host England, Scotland visit France, and Ireland head to Italy.
Pete Horne is preferred to Adam Hastings in Scotland's starting line-up for their clash with France in Paris.
Josh Strauss has lost his passport, but the Scotland back row has been given the stamp of approval to travel to Paris.
Morgan Parra and Camille Lopez's absence from France's Six Nations squad is a sporting decision and nothing more, says Jacques Brunel.
Finn Russell has not satsified the requirements of his graduated return-to-play protocol and will miss Scotland's clash with France.
Full-back Thomas Ramos will make his first start for France, who have a new half-back pairing for the Six Nations clash against Scotland.
Gregor Townsend has added six players to Scotland's squad ahead of the France Six Nations trip, but Stuart Hogg is out.
Having lost Ryan Wilson for the rest of the Six Nations earlier this week, Scotland may also have to cope without Huw Jones.
Gregor Townsend is optimistic there will be good news on Stuart Hogg's shoulder injury when he visits a specialist.
Ryan Wilson will play no further part in the Six Nations, while Stuart Hogg and Huw Jones will be assessed this week.