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George North scored the only try and Dan Biggar answered his critics in a 13-6 win over England that put Wales top of the world rankings.
Dan Biggar, James Davies and Jake Ball come into the Wales side as they eye revenge against England in Cardiff.
England's squad are aware the hard work in preparation for the World Cup in Japan has just started, according to head coach Eddie Jones.
Gareth Anscombe will play no part in Wales' Rugby World Cup campaign after suffering an ACL injury against England.
England head coach Eddie Jones took a swipe at the governing body six weeks before the Rugby World Cup over the tackle laws.
Wales head coach Warren Gatland had injury worries to contend with following a 33-19 World Cup warm-up defeat to England at Twickenham.
England were too good for a strong Wales side at Twickenham, where Gareth Anscombe and Tom Curry sustained injury blows.
Joe Cokanasiga, Jonathan Joseph and Lewis Ludlam have come into the England team due to a trio of injuries.
All Blacks captain Kieran Read says potentially losing world number one status is "not even part of our equation".
Eddie Jones has given some potential Rugby World Cup bolters a chance to show what they can do against Wales.
England start their Rugby World Cup preparation when they take on Wales on Sunday, and four players have been cut from Eddie Jones' squad.
Wales have confirmed flanker Taulupe Faletau will miss the Rugby World Cup after sustaining a clavicle injury.
Alun Wyn Jones will remain on course to break the all-time record for international caps after extending his Welsh Rugby Union contract.
Departing Wales head coach Warren Gatland will take charge of the British and Irish Lions for a third time.
Departing Wales head coach Warren Gatland will take charge of the British and Irish Lions for a third time.
Warren Gatland will make a swift return to Wales to take on Wayne Pivac's side with the Barbarians in November.
