Alessandro Zanni comes back in for Dean Budd in Italy's only change for their clash with Scotland.
A wing injury crisis has led to Gael Fickou moving out wide against Wales, with centre Virimi Vakatawa back in the side.
Wayne Pivac has made two changes to his starting line-up to face France, Gareth Davies and Ross Moriarty getting the nod.
Eddie Jones says Manu Tuilagi should be fit to return against Ireland, while fellow centre Henry Slade will be monitored.
Caelan Doris has recovered from a head injury, but the Ireland number eight has to settle for a place on the bench against England.
Scotland, who are yet to score a try in this year's Six Nations, have made three changes to their XV to face Italy in...
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Jordan Petaia, who saw his 2019 season blighted by a foot injury, has suffered another setback that will end his Super Rugby season.
Top 14 leaders Bordeaux-Begles have agreed a two-year deal with Ben Lam, who will join from the Hurricanes at the end of the campaign.
Hallam Amos returns to the Wales squad for this weekend's Six Nations clash with pace-setters France, replacing Cardiff team-mate Owen Lane.
Director of rugby Dai Young is on his way out of Wasps after nine years in charge, the Premiership club have announced.
Mako Vunipola has flown to Tonga and will not be available for England's Six Nations encounter with unbeaten Ireland this weekend.
Racing 92 stretched their Top 14 winning run to five matches with a dramatic defeat of Toulouse.
Henry Purdy and Lewis Thiede touched down within two minutes of one another to see Bristol Bears past Northampton Saints.
Scotland have called up the fit-again Sam Skinner and Matt Fagerson ahead of their clash with Italy in Rome on February 22.
Jamie George said he is not leaving Saracens earlier this week and England team-mate Elliot Daly is also staying put.
The Reds squandered a promising lead in Argentina as the Jaguares claimed their second win of the season.