Rey Lee-Lo was fortunate to escape with a booking for a high tackle on Russia's Vasily Artemyev, but has now been banned for three matches.
Japan eased past Russia in their Rugby World Cup opener but will face a far sterner test against Ireland, who will be without Johnny Sexton.
A much-changed South Africa will face Namibia as Rassie Erasmus' side look to kick-start their Rugby World Cup campaign.
England have been perfect in their Rugby World Cup campaign so far, according to Eddie Jones, whose side thrashed the United States 45-7.
Canada were unable to run Italy close again as Conor O'Shea's team scored seven tries in a 48-7 victory at the Rugby World Cup.
Eddie Jones made 10 changes to the England XV and saw his side overpower the United Sates in Pool C.
Sam Warburton can see Wales going all the way to the Rugby World Cup final if they beat Australia on Sunday.
Having recorded another bonus-point win, Italy's players will be given a chance to let their hair down before facing South Africa.
Ireland coach Joe Schmidt has made four changes for the Pool A clash against hosts Japan, with Jack Carty starting at fly-half.
Among the favourites to win the Webb Ellis Cup, England do not have a glaring weakness in their team, according to USA coach Gary Gold.