The Bulls went top of the South African Conference by brushing aside the Sharks as the Lions held off the Jaguares.
England responded to their Six Nations loss versus Wales with an emphatic defeat Italy, setting up an intriguing final weekend.
Gregor Townsend was left to reflect on a missed opportunity after Scotland failed to derail Wales' quest for a Grand Slam.
Scotland dominated the second half at Murrayfield and Warren Gatland admitted his Wales side got "a little bit lucky" as they prevailed.
Victory over Ireland in the final round of the Six Nations would secure a Grand Slam for Wales after Warren Gatland's men overcame Scotland.
The 2019 Rugby World Cup is set to represent Rory Best's swansong, with the hooker "fairly sure" he will retire following the tournament.
Follow all the weekend’s Super Rugby matches live on Keo.co.za Live Match Centre. There were wins for the Hurricanes, Rebels, Crusaders, Blues, Waratahs, Lions and Bulls....
The Crusaders were far too good for the Chiefs on Saturday, while the Blues claimed a first win in 2019 and the Waratahs beat the Reds.
Saracens suffered a second defeat in three at Bath, while Sale Sharks piled on the agony for Leicester Tigers.
Lewis Moody says England will be wounded from a defeat to Wales that he says should never have happened.