Conor O'Shea has made two changes to his Italy XV ahead of hosting Wales, with Edoardo Padovani and Nicola Quaglio coming in.
Ireland will have to do without Robbie Henshaw when they take on Scotland, so Chris Farrell comes into the side at Murrayfield.
Blair Kinghorn was not able to keep his place in the Scotland side to take on Ireland, with the experienced Sean Maitland taking his spot.
Warren Gatland has made 10 changes to his starting line-up for the clash against Italy, with Jonathan Davies named as captain.
David Wessels will remain in charge of the Rebels until 2021 after the Super Rugby franchise extended his deal.
England have included Brad Shields, Joe Launchbury and Joe Cokanasiga in their 25-man squad to face France at Twickenham.
England fared well without Dylan Hartley in Ireland, but defence coach John Mitchell is keen to have the co-captain back involved.
Elliot Daly is a fantastic signing for Saracens and his skills will only develop at Allianz Park, says Lewis Moody.
Lewis Moody is sure England can cope without Maro Itoje due to the amount of options they have in the second row.
A day on from Wasps confirming Elliot Daly is set to leave the club, Saracens have announced their signing of the England back.