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Lyon scored all five tries in the second half in a rout of Stade Francais, while Racing 92 claimed their fourth consecutive win.
Eddie Jones backed Owen Farrell after England's narrow victory against South Africa.
Clermont Auvergne could only draw with lowly Grenoble and Toulouse took advantage by putting Bordeaux-Begles to the sword in the Top 14.
Jordan Larmour grasped his first opportunity to start for Ireland with both hands, scoring three tries and laying on another in Chicago.
Warren Gatland saw room for improvement but was encouraged by the way Wales saw off Scotland to win the Doddie Weir Cup.
There were wins for Connacht and Ulster in Saturday's Pro14 action.
Australian referee Angus Gardener should never again referee an international match. His decision not to card Owen Farrell for an obvious shoulder charge on Andre Esterhuizen...
Eben Etzebeth suffered what appeared to be an ankle injury early in the second half of the Springboks' defeat against England.
South Africa dominated England in the second half, but Eddie Jones was pleased with the way his side hung in there and fought back.
South Africa paid the price for letting England off the hook at Twickenham, where Eddie Jones' men gained revenge for a series loss in June.
