Toulouse are now unbeaten in 14 Top 14 matches after grinding it out at La Rochelle, while Racing 92 got the better of Bordeaux.
Bath were well beaten at Sandy Park as Exeter Chiefs sealed a top-four spot by extending their winning streak to four matches.
London-based Shaun Edwards admits a role with England would have its perks after it emerged he has not officially taken the Wigan job.
After three straight losses to start the Super Rugby season, the Reds made it back-to-back wins by beating the Brumbies.
Bonus-point wins for Glasgow Warriors and Munster mean the top two in Conference A remain three points apart.
Tries from Carl Fearns, Mickael Ivaldi and Thibaut Regard helped Lyon get back to winning ways in Saturday's Top 14 action.
Shaun Edwards would be welcomed back at Wasps if he opts out of coaching Wigan Warriors, says director of rugby Dai Young.
Two tries from Will Skelton helped Premiership title hopefuls Saracens fight back to beat Harlequins 27-20 at London Stadium on Saturday.
Yuji Watase, the Sunwolves CEO, has criticised SANZAAR's decision to axe the Japanese side from Super Rugby.
The Sharks recorded a home win over the Rebels, while the Chiefs cruised to victory against the Bulls to kickstart their Super Rugby season.