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For the second time in two days, a side racked up a century of points in the Challenge Cup as Bristol Bears routed Enisei 107-19.
At the age of just 28, former Springbok Patrick Lambie has retired from professional rugby, his club Racing 92 have announced.
England's preparations for the Six Nations have been hit by the fact captain Owen Farrell needs surgery.
Northampton scored 17 tries in a record victory as they beat Timisoara Saracens 111-3 to reach the European Challenge Cup quarter-finals.
Both Edinburgh and Glasgow Warriors are through to the European Champions Cup quarter-finals due to the former's 19-10 win over Montpellier.
Billy Vunipola will take more motivation from England's response to the 2015 Rugby World Cup than from the disappointment.
Cheetahs secured a dramatic 24-17 victory over South African rivals Southern Kings after Luan de Bruin touched down in the 85th minute.
Jack Nowell's versatility could be put to the test after Eddie Jones revealed the 25-year-old may feature for England in the pack.
Owen Farrell can thrive as captain in the absence of Dylan Hartley as England begin their Six Nations campaign against Ireland.
Owen Farrell will be England's sole captain against Ireland, with Dylan Hartley unavailable for the start of the Six Nations due to injury.
