Johnny Sexton has played only three matches since the Rugby World Cup, but Andy Farrell saw an "outstanding" display from Ireland's captain.
Johnny Sexton and Jordan Larmour have been joined by uncapped number eight Caelan Doris in Ireland's team to face Scotland.
Johnny Sexton expects to lead Ireland against Scotland in Dublin and Jordan Larmour is expected to be in contention.
Lyon are reportedly targeting Ireland fly-half Johnny Sexton, but Leinster insist there has been no suggestion he will leave the province.
Leinster head coach Leo Cullen is unsure how long fly-half Johnny Sexton will be out of action.
Ireland head coach Joe Schmidt says Johnny Sexton will be fit to face Samoa despite playing just one half of the win against Russia.
Robbie Henshaw is yet to feature for Ireland at the 2019 Rugby World Cup and Joe Schmidt remains reluctant to risk him against Russia.
Only four players remain from Ireland's stunning defeat to Japan, as Johnny Sexton captains his country for the first time against Russia.
Rugby World Cup hosts Japan will become the latest outfit to attempt to unsettle Ireland superstar Johnny Sexton this weekend.
Rory Best began his final Rugby World Cup campaign with a try as Ireland accelerated away from Scotland en route to an opening win.
Johnny Sexton and Rory Best led the way as Ireland's thumping win over Scotland affirmed their credentials as Rugby World Cup challengers.
Johnny Sexton was taken off with injury against Scotland earlier this year and Gregor Townsend's men intend to get physical again.
Ireland's talisman Johnny Sexton says he was "blessed' to overcome a thumb injury in time to make Joe Schmidt's Rugby World Cup squad.
Ross Byrne will start Ireland's meeting with England at fly-half as Johnny Sexton and Joey Carbery struggle with injury.
The European Champions Cup final defeat to Saracens was hard to take for Leinster, but Johnny Sexton says they will bounce back.
There will be two Sextons in the Pro14 next season after Johnny's younger brother Jerry agreed to join Southern Kings from Jersey Reds.