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After almost a year out of action due to a back injury, Leinster and Ireland's Jamie Heaslip has been forced to call it quits.
Reports Sonny Bill Williams could return to the Sydney Roosters were rubbished by the NRL club's chairman, Nick Politis.
The Reds will definitely be without captain Scott Higginbotham for their next two matches, but Lukhan Tui's availability remains unclear.
After Owen Farrell and Ryan Wilson appeared to be involved in a pre-match scuffle at Murrayfield, Six Nations Rugby will investigate.
Eddie Jones apologised to England fans after their Six Nations Grand Slam hopes went up in smoke at Murrayfield against an inspired Scotland
Warren Gatland dismissed Wales' Six Nations chances after losing in Ireland and will look to blood new players into the team next time out.
John Barclay hailed Finn Russell as one of the best fly-halves in world rugby after he inspired Scotland to a stunning win over England.
Ireland will assess their performance after they survived a late scare to beat Wales 37-27 at the Aviva Stadium.
Scotland have not beaten England for a decade and Lee Mears does not expect them to put that right at Murrayfield.
Former England lock Simon Shaw says facing Scotland at Murrayfield will be a "very tough proposition" for the Six Nations holders.
England cannot afford to give Scotland the scent of victory in the closing stages at Murrayfield, says Martin Johnson.
England have not lost to Scotland for a decade and John Barclay knows his side face a "big challenge" to end that dismal run.
Rory Best believes Johnny Sexton will start for Ireland despite him receiving treatment on his back on Friday.
Eddie Jones has turned England into a major force, but said to himself "Goodness me, what have I got myself into here?" early in his reign.
Owen Farrell missed some training sessions ahead of England's Six Nations meeting with Scotland but Eddie Jones has cast aside any concerns.
Wales will be coached by Warren Gatland for the 100th time on Saturday and we have crunched the numbers behind his tenure.
